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Table 1 Total Sod activity of Staphylococcus aureus clinical isolates.

From: Superoxide dismutase is upregulated in Staphylococcus aureus following protoporphyrin-mediated photodynamic inactivation and does not directly influence the response to photodynamic treatment

S. aureus strain

Strain response to PDIΔ

Total Sod activity [U/mg of cell proteins]1

Total Sod activity [U/mg of cell proteins]2

Sod activity increase [× fold]

  

Before PDI 3

After PDI 3

Before PDI 3

After PDI 3

 
 

MRSA

     

472

S

1494 ± 517

492 ± 96

16.7 ± 10.4

66.6 ± 5.8

3.9

2002

R

2006 ± 312

1247 ± 154

41.8 ± 6.5

43.3 ± 5.2

1.0

80/0

S

1604 ± 404

680 ± 93

24.6 ± 6.2

113.4 ± 15.5

4.6

4246

R

1703 ± 720

1807 ± 591

11.6 ± 4.9

34.4 ± 10.3

2.9

 

MSSA

     

1397

R

2234 ± 235

1046 ± 48

32.8 ± 3.4

28.5 ± 0.86

0.8

7259

R

1957 ± 805

1375 ± 178

46.6 ± 19.2

42.3 ± 5.3

0.9

2288

S

3596 ± 427

3583 ± 488

27.8 ± 3.3

137.2 ± 14.2

4.9

5491

S

2070 ± 318

2426 ± 42

25.2 ± 3.9

86.5 ± 1.5

3.4

  1. 1- the given numbers are mean values of 3 measurements ± standard deviation, absolute values are given
  2. 2 - values normalized with respect to the number of c.f.u. (colony forming units)
  3. 3 - PDI - Photodynamic inactivation performed with 50 μM protoporphyrin IX, light dose of 12 J/cm2, 624 nm red light.
  4. MRSA - Multiresistant Staphylococcus aureus; MSSA - Multisensitive Staphylococcus aureus
  5. ΔS - sensitive, R - resistant