TY - JOUR AU - Fagerlund, Annette AU - Lindbäck, Toril AU - Granum, Per Einar PY - 2010 DA - 2010/11/30 TI - Bacillus cereus cytotoxins Hbl, Nhe and CytK are secreted via the Sec translocation pathway JO - BMC Microbiology SP - 304 VL - 10 IS - 1 AB - Bacillus cereus and the closely related Bacillus thuringiensis are Gram positive opportunistic pathogens that may cause food poisoning, and the three secreted pore-forming cytotoxins Hbl, Nhe and CytK have been implicated as the causative agents of diarrhoeal disease. It has been proposed that the Hbl toxin is secreted using the flagellar export apparatus (FEA) despite the presence of Sec-type signal peptides. As protein secretion is of key importance in virulence of a microorganism, the mechanisms by which these toxins are secreted were further investigated. SN - 1471-2180 UR - https://doi.org/10.1186/1471-2180-10-304 DO - 10.1186/1471-2180-10-304 ID - Fagerlund2010 ER -