Comparison of the structure of PAI in V. parahaemolyticus, V. cholerae and V. mimicus. Schematic representation of the structure of the PAI in V. parahaemolyticus RIMD2210633 (containing T3SS2α) and TH3996 (containing T3SS2β) strains and in V. cholerae AM-19226 (containing T3SS2α) and 1587 (containing T3SS2β) strains. Names of the various V. parahaemolyticus and V. cholerae strains are shown along the left side. Black boxes represent core chromosomal genes flanking the PAI region in V. parahaemolyticus or V. cholerae strains. Horizontally striped boxes represent sialic acid metabolism regions, and the checkered box represents the urease gene cluster, while diagonally striped and dotted boxes represent T3SS2 regions, and white boxes other ORFs in PAI regions. White circles represent the ORFs which were tested for the presence or absence of ORFs in V. mimicus strains, and black circles indicate the presence of such ORFs.