Identification of Lactobacillus plantarum genes modulating the cytokine response of human peripheral blood mononuclear cells

Table 3 Relative differences in cytokine amounts between L. plantarum WCFS1 wild-type and deletion mutants.

^aL. plantarum WCFS1 deletion mutant measured in the PBMC assay.
^bPhase of growth from which L. plantarum cells were harvested (log = exponential phase; stat = stationary phase).
^cThe value is the average difference in ²Log cytokine amounts induced by wild-type L. plantarum and mutant cells harvested in the same phase of growth (log or stat). A positive value indicates an increase in IL-10 levels produced by PBMCs in response to mutant L. plantarum compared to the wild-type cells. Calculations of t-test p-values and adjusted (adj.) p-values are described in the text (Materials and Methods). * (0.01 < p < 0.05); ** (0.002 < p < 0.01); *** (p < 0.002) for the adj. p-values.

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