Figure 3

Model of the H-NS-dependent regulatory network in flagella and acid stress control. At the top, H-NS positively controls motility and represses acid stress resistance. Genes in cross symbol are directly activated by H-NS; in rectangle: directly repressed by H-NS; in circle: indirectly repressed by H-NS. Regulatory proteins are indicated with upper case. Orange filling: flagellum synthesis process; Pink filling: glutamate-dependent acid resistance process; Blue filling: arginine-dependent acid resistance process; Red filling: lysine-dependent acid resistance process; Green filling: genes involved in three different acid resistance processes. Gene names in yellow indicate the direct targets of RcsB-P/GadE complex placed at the centre of this regulatory cascade. A positive effect on transcription is indicated by arrows and a negative regulatory effect is indicated by blunt ended lines. Direct regulation is indicated by solid lines. Indirect regulation is indicated by dashed lines. Previously published results are included in the scheme: [1–3, 5–7, 10, 16, 32–40].