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Table 6 Highly variable P. gingivalis genomic regions

From: The core genome of the anaerobic oral pathogenic bacterium Porphyromonas gingivalis

Variable region

Location

Gene content of the region

Region 1

PG0109-PG0118

Capsular polysaccharide biosynthesis locus [27, 28]

Region 2

PG0814-PG0875

Potential pathogenicity island [28]. Many DNA mobilization proteins

Region 3

PG1435-PG1533

Potential pathogenicity island [28]. Many transposon related genes.

Region 4

PG0185-PG0187

Virulence associated ragA-ragB locus [46] highly variable in strains other than W83 and ATCC49417

Region 5

PG0456-PG0461

PHP domain protein, transposases

Region 6

PG0542-PG0546

transcriptional regulator, type 1 restriction modification gene

Region 7

PG0741-PG0742

PgaA and hypothetical protein

Region 8

PG1107-PG1113

Integrase/mobilization, hypothetical proteins

Region 9

PG1200-PG1206

Transcriptional regulator, DNA binding protein, hypothetical proteins

Region 10

PG2134-PG2136

Lipoproteins, hypothetical proteins