Venn diagram of differentially expressed THP-1 genes. A venn diagram visualization showing 784 and 901 differentially expressed host genes in C. burnetii infected THP-1 cells under mock (- CAM) and CAM treated (+ CAM) conditions respectively, as determined by oligonucleotide microarray analysis. Comparisons between differentially expressed genes of -CAM with the gene summary list of + CAM (>0 fold Δ = 2584 genes) and differentially expressed genes of + CAM with the gene summary list of -CAM (>0 fold Δ = 2557 genes) are also shown. The intersections (areas of overlap) indicate genes regulated in common under both conditions. Twenty-eight of the differentially expressed genes in - CAM and thirty-five of the differentially expressed genes in + CAM are modulated by C. burnetii protein synthesis (>2 fold difference). Of these, twenty-seven are common between the two conditions, while eight and one genes are uniquely expressed in +CAM and -CAM conditions, respectively.