Table 1 Functional classification of differentially expressed genes under nitrogen starvation in X. fastidiosa.
Functional Category* | Temporal series§ | ||
|---|---|---|---|
2 h | 8 h | 12 h | |
Intermediary metabolism (25/34) # | |||
Degradation (5/3) | 2/0 | 1/3 | 2/2 |
Central intermediary metabolism (5/10) | 4/0 | 2/7 | 3/6 |
Energy metabolism, carbon (3/17) | 1/2 | 3/16 | 0/14 |
Regulatory functions (12/4) | 4/1 | 9/2 | 5/2 |
Biosynthesis of small molecules (28/25) | |||
Amino acids biosynthesis (13/10) | 9/1 | 8/7 | 3/4 |
Nucleotides biosynthesis (2/5) | 0/0 | 1/2 | 2/5 |
Sugars and sugar nucleotides biosynthesis (0/1) | 0/0 | 0/1 | 0/0 |
Cofactors, prosthetic groups, carriers biosynthesis (8/5) | 2/0 | 6/4 | 2/3 |
Fatty acid and phosphatidic acid biosynthesis (4/4) | 2/0 | 2/2 | 1/3 |
Polyamines biosynthesis (1/0) | 0/0 | 0/0 | 1/0 |
Macromolecule metabolism (28/37) | |||
DNA metabolism (8/8) | 1/1 | 5/4 | 7/4 |
RNA metabolism (17/13) | 3/0 | 13/11 | 11/9 |
Protein metabolism (3/16) | 0/6 | 1/15 | 2/13 |
Cell structure (12/9) | |||
Membrane components (6/3) | 2/0 | 1/1 | 3/2 |
Murein sacculus, peptidoglycan (2/0) | 1/0 | 0/0 | 1/0 |
Surface polysaccharides, lipopolysaccharides, and antigens (2/1) | 2/0 | 0/1 | 1/0 |
Surface structures (2/5) | 2/0 | 2/4 | 1/5 |
Cellular processes (9/15) | |||
Transport (8/12) | 4/0 | 6/5 | 3/11 |
Cell division (1/3) | 1/0 | 1/3 | 0/1 |
Mobile genetic elements (16/7) | |||
Phage-related functions and prophages (8/1) | 2/0 | 8/1 | 6/0 |
Plasmid-related functions (7/6) | 3/0 | 6/6 | 3/2 |
Transposon- and intron-related functions (1/0) | 0/0 | 0/0 | 1/0 |
Pathogenicity, virulence, and adaptation (9/13) | 1/3 | 6/8 | 5/9 |
Hypothetical (122/52) | 30/5 | 73/34 | 69/31 |
ORFs with undefined category (3/4) | 1/0 | 2/2 | 0/2 |
Total (252/196) | 77/19 | 156/139 | 132/128 |