Table 1 Comparison of pncA sequencing, the pyrazinamidase assay, and the MGIT 960 system for PZA susceptibility testing.
M. tb strains (total no. of isolates) | MGIT (S) PZase (pos) pncA (wt) | MGIT (S) PZase (pos) pncA (mut) | MGIT (R) PZase (neg) pncA (mut) | MGIT (R) PZase (pos) pncA (wt) | MGIT (R) PZase (pos) pncA (mut) |
|---|---|---|---|---|---|
Susceptible (50) | 46 | 1 | - | 2 | 1 |
MDR-TB (100) | 42 | 9 | 34 | 11 | 4 |