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Table 1 Comparison of pncA sequencing, the pyrazinamidase assay, and the MGIT 960 system for PZA susceptibility testing.

From: Surveillance of pyrazinamide susceptibility among multidrug-resistant Mycobacterium tuberculosis isolates from Siriraj Hospital, Thailand

M. tb strains
(total no. of isolates)
MGIT (S)
PZase (pos)
pncA (wt)
MGIT (S)
PZase (pos)
pncA (mut)
MGIT (R)
PZase (neg)
pncA (mut)
MGIT (R)
PZase (pos)
pncA (wt)
MGIT (R)
PZase (pos)
pncA (mut)
Susceptible (50) 46 1 - 2 1
MDR-TB (100) 42 9 34 11 4
  1. S; susceptible, R; resistant, PZase; pyrazinamidase assay, MGIT; BACTEC MGIT 960 method, pos; positive, neg; negative, wt; wild-type, mut; mutant