Skip to main content

Table 2 Parameters from equation (11) used in the simulations of Figures 6 and 7

From: Biphasic toxicodynamic features of some antimicrobial agents on microbial growth: a dynamic mathematical model and its implications on hormesis

 

growth model

DRX model

DRr model

cases

 

pop 1 a

pop 2 a

 

pop 1

pop 2

 

pop 1

pop 2

fig 6A

X 0

0.100

-

K X

-

-

K r

0.900

-

 

r 0

0.100

-

m X

-

-

m r

10.000

-

 

X m

1.000

-

a X

-

-

a r

1.500

-

fig 6B

X 0

0.100

-

K X

0.001

-

K r

-

-

 

r 0

0.100

-

m X

10.000

-

m r

-

-

 

X m

1.000

-

a X

1.500

-

a r

-

-

fig 6C

X 0

0.150

-

K X

-

-

K r

0.800

-

 

r 0

0.150

-

m X

-

-

m r

30.000

-

 

X m

1.000

-

a X

-

-

a r

1.500

-

fig 7A

X 0

0.050

0.050

K X

-

-

K r

0.600

1.000 S

 

r 0

0.500

0.025

m X

-

-

m r

4.000

4.000 S

 

X m

1.000

1.000

a X

-

-

a r

1.500

1.500 S

fig 7B

X 0

0.200

0.050

K X

0.002

-

K r

0.600

1.000 S

 

r 0

0.150

0.050

m X

4.000

-

m r

3.000

4.000 S

 

X m

1.000

1.000

a X

1.500

-

a r

1.500

1.500 S

  1. In 6C, the dose is considered as the ratio of initial effector level to biomass in each time instant. In the rest of the cases the habitual criterion is applied (dose as initial concentration of the effector).
  2. (a): populations 1 and 2, as defined by means of the parameters of growth and DR models.
  3. (S): parameters corresponding to stimulatory responses.