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Table 1 The percentage of P. aeruginosa isolates that were non-susceptible to antimicrobials and demonstrated overexpression of efflux genes and ampC β-lactamase, coupled with oprD down-regulation.

From: Efflux pumps expression and its association with porin down-regulation and β-lactamase production among Pseudomonas aeruginosa causing bloodstream infections in Brazil

Antimicrobial

Non-susceptible (n= 59)

% of isolates (n)

  

ABM+ (16)

XY+ (30)

AmpC+ (07)

OprD- (41)

Aztreonam

21 (35.6)

56.3 (09)

43.3 (13)

71.4 (05)

34.1 (14)

Imipenem

31 (52.5)

56.3 (09)

80.0 (24)

71.4 (05)

65.9 (27)

Meropenem

31 (52.5)

62.5 (10)

80.0 (24)

71.4 (05)

63.4 (26)

Cefepime

30 (50.8)

56.3 (09)

80.0 (24)

85.7 (06)

58.5 (24)

Ceftazidime

33 (55.9)

50.0 (08)

76.7 (23)

100 (07)

63.4 (26)

Amikacin

35 (59.3)

68.8 (11)

86.7 (26)

57.1 (04)

70.7 (29)

Gentamicin

40 (67.8)

75.0 (12)

86.7 (26)

57.1 (04)

65.9 (27)

Ciprofloxacin

38 (64.4)

81.3 (13)

86.7 (26)

85.7 (06)

63.4 (26)

  1. The abbreviations ABM+, XY+ and AmpC+ designate MexAB-OprM, MexXY, and AmpC overexpression, respectively.
  2. OprD -: OprD porin down-regulation.