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Table 1 Summary of E. col i K-12 biofilm antibiotic tolerance robustness analyses

From: Robustness analysis of culturing perturbations on Escherichia coli colony biofilm beta-lactam and aminoglycoside antibiotic tolerance

 

kanamycin

ampicillin

perturbation

low LR1

high LR1

ΔLR2

low LR1

high LR1

ΔLR2

glucose

1.3

8.8

7.5

1.5

7.6

6.1

temperature

8.4

9.5

1.1

0.5

5.8

5.3

AI-2 QS

8.8

9.9

1.1

0.3

1.5

1.2

culture stage

1.7

8.8

7.1

0.1

4.6

4.5

glucose + temp.

1.3

9.5

8.2

0.5

7.6

7.1

glucose+AI-2 QS

0.8

9.9

9.1

0.3

7.6

7.3

  1. 1. For each set of perturbation data, the lowest and highest log reduction (LR) in cfu's/biofilm are listed. The perturbed conditions are compared to biofilm cultures grown on LB only medium at 37°C. cfu = colony forming unit.
  2. 2. ΔLR = the maximum observed range in log reductions (LR) between the base scenario
  3. and the perturbed culturing condition.