Table 1 Effects of antibiotics on the growth and DON-transforming activity of bacteria from the large (LIC) or small (SIC) intestine.
Antibiotics | Final concen (μg/mL) | LIC-S2 |  | LIC-S3 |  | SIC-S2 |  | SIC-S3 |  |
|---|---|---|---|---|---|---|---|---|---|
| Â | Â | Growth | DON to DOM-1 (%) | Â | Â | Growth | DON to DOM-1 (%) | Â | Â |
No antibiotic | 0 | +++ | 100.0 | N/A | Â | +++ | 100.0 | +++ | 100.0 |
Streptomycin | 100 | +++ | 49.3 | +++ | 25.6 | +++ | 44.3 | +++ | 5.8 |
| Â | 50 | +++ | 100.0 | +++ | 30.8 | +++ | 48.7 | +++ | 11.4 |
| Â | 5 | +++ | 100.0 | +++ | 100.0 | +++ | 100.0 | +++ | 100.0 |
Gentamicin | 80 | +++ | 18.1 | +++ | 6.0 | ++ | 44.0 | +++ | 7.1 |
| Â | 40 | +++ | 23.5 | +++ | 6.5 | +++ | 44.8 | +++ | 7.4 |
| Â | 5 | +++ | 100.0 | +++ | 22.5 | +++ | 46.5 | +++ | 6.8 |
Bacitracin | 60 | ++ | 16.2 | ++ | 0.0 | +++ | 45.0 | +++ | 8.0 |
| Â | 30 | ++ | 16.1 | ++ | 2.5 | +++ | 45.0 | +++ | 8.8 |
| Â | 5 | +++ | 15.8 | +++ | 3.9 | +++ | 47.0 | +++ | 11.9 |
No antibiotic | 0 | +++ | 100.0 | +++ | 100.0 | +++ | 100.0 | +++ | 100.0 |
Penicillin G | 100 | + | 12.1 | +++ | 1.5 | ++ | 100.0 | + | 35.5 |
| Â | 50 | + | 12.7 | +++ | 7.4 | ++ | 100.0 | + | 44.1 |
| Â | 5 | ++ | 100.0 | +++ | 100.0 | +++ | 100.0 | +++ | 100.0 |
Virginiamycin | 20 | +++ | 100.0 | +++ | 100.0 | +++ | 100.0 | +++ | 100.0 |
| Â | 10 | +++ | 100.0 | +++ | 100.0 | +++ | 100.0 | +++ | 100.0 |
| Â | 5 | +++ | 100.0 | +++ | 100.0 | +++ | 100.0 | +++ | 100.0 |
Lincomycin hydrochloride | 60 | +++ | 100.0 | +++ | 100.0 | +++ | 31.3 | +++ | 3.6 |
| Â | 30 | +++ | 100.0 | +++ | 100.0 | +++ | 100.0 | +++ | 100.0 |
| Â | 5 | +++ | 100.0 | +++ | 100.0 | +++ | 47.3 | +++ | 100.0 |
No antibiotic | 0 | +++ | 100.0 | +++ | 100.0 | +++ | 100.0 | +++ | 100.0 |
Salinomycin | 80 | +++ | 16.7 | +++ | 2.0 | +++ | 55.2 | +++ | 8.9 |
| Â | 40 | +++ | 18.0 | +++ | 4.0 | +++ | 89.2 | +++ | 80.9 |
| Â | 5 | +++ | 16.8 | +++ | 100.0 | +++ | 100.0 | +++ | 100.0 |
Vancomycin | 30 | +++ | 15.9 | +++ | 2.5 | ++ | 46.2 | +++ | 9.6 |
| Â | 15 | +++ | 15.0 | +++ | 2.2 | ++ | 44.9 | +++ | 10.5 |
| Â | 5 | +++ | 38.5 | +++ | 13.2 | ++ | 46.8 | +++ | 9.7 |
Carbadox | 50 | +++ | 16.4 | ++ | 3.5 | ++ | 27.7 | +++ | 3.9 |
| Â | 25 | +++ | 100.0 | +++ | 45.2 | +++ | 100.0 | +++ | 52.7 |
| Â | 5 | +++ | 100.0 | +++ | 78.7 | +++ | 100.0 | +++ | 100.0 |
Tylosin | 80 | +++ | 100.0 | +++ | 100.0 | +++ | 100.0 | +++ | 79.4 |
| Â | 40 | +++ | 100.0 | +++ | 100.0 | +++ | 100.0 | +++ | 92.2 |
| Â | 5 | +++ | 100.0 | +++ | 94.5 | +++ | 100.0 | +++ | 100.0 |