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Table 1 Statistical importance of discriminating TTGE bands

From: A distinctive 'microbial signature' in celiac pediatric patients

CD patients vs Controls (PC1)

TTGE band §

Active + Inactive (%)

Control (%)

VIP

P value (a)

26 (E.coli)

92.1

20.0

2.023

< 0.0001

18 (P.distasonis)

86.8

20.0

1.867

< 0.0001

39 (P.distasonis)

89.5

20.0

1.847

0.0001

35

73.7

0.0

1.802

< 0.0001

1 (B.vulgatus)

89.5

20.0

1.755

0.001

13

57.9

0.0

1.580

0.000

15

63.2

0.0

1.535

0.001

29

60.5

0.0

1.516

0.001

3

52.6

0.0

1.311

0.003

6

60.5

0.0

1.194

0.010

22

52.6

10.0

1.151

0.007

16

39.5

0.0

1.024

0.018

Active CD patients vs Inactive CD patients (PC2)

TTGE band §

Active (%)

Inactive (%)

VIP

P value (b)

8 (P.distasonis)

31.6

0.0

1.691

0.009

1 (B.vulgatus)

84.2

94.7

1.687

0.026

6

47.4

73.7

1.667

0.089

7

26.3

0.0

1.522

0.015

21

21.1

0.0

1.507

0.023

26

94.7

89.5

1.498

0.474

39

89.5

89.5

1.475

1.000

13

73.7

42.1

1.316

0.054

18

94.7

78.9

1.299

0.032

35

78.9

68.4

1.271

0.255

12

36.8

10.5

1.258

0.049

15

68.4

57.9

1.079

0.386

5

36.8

15.8

1.056

0.083

29

68.4

52.6

1.054

0.237

19

47.4

63.2

1.046

0.237

9

78.9

94.7

1.031

0.255

  1. § Bands were self numbered according to the order of appearance (top-bottom) on the TTGE gel and are listed in descending order of importance (VIP) in the PLS-DA model. Between parentheses are reported the species used in the gel marker that run parallel to specific TTGE bands.
  2. (a) Mann-Whitney U-test, α = 0.05
  3. (b) Wilcoxon signed rank test, α = 0.05