Skip to main content

Advertisement

Table 1 Statistical importance of discriminating TTGE bands

From: A distinctive 'microbial signature' in celiac pediatric patients

CD patients vs Controls (PC1)
TTGE band § Active + Inactive (%) Control (%) VIP P value (a)
26 (E.coli) 92.1 20.0 2.023 < 0.0001
18 (P.distasonis) 86.8 20.0 1.867 < 0.0001
39 (P.distasonis) 89.5 20.0 1.847 0.0001
35 73.7 0.0 1.802 < 0.0001
1 (B.vulgatus) 89.5 20.0 1.755 0.001
13 57.9 0.0 1.580 0.000
15 63.2 0.0 1.535 0.001
29 60.5 0.0 1.516 0.001
3 52.6 0.0 1.311 0.003
6 60.5 0.0 1.194 0.010
22 52.6 10.0 1.151 0.007
16 39.5 0.0 1.024 0.018
Active CD patients vs Inactive CD patients (PC2)
TTGE band § Active (%) Inactive (%) VIP P value (b)
8 (P.distasonis) 31.6 0.0 1.691 0.009
1 (B.vulgatus) 84.2 94.7 1.687 0.026
6 47.4 73.7 1.667 0.089
7 26.3 0.0 1.522 0.015
21 21.1 0.0 1.507 0.023
26 94.7 89.5 1.498 0.474
39 89.5 89.5 1.475 1.000
13 73.7 42.1 1.316 0.054
18 94.7 78.9 1.299 0.032
35 78.9 68.4 1.271 0.255
12 36.8 10.5 1.258 0.049
15 68.4 57.9 1.079 0.386
5 36.8 15.8 1.056 0.083
29 68.4 52.6 1.054 0.237
19 47.4 63.2 1.046 0.237
9 78.9 94.7 1.031 0.255
  1. § Bands were self numbered according to the order of appearance (top-bottom) on the TTGE gel and are listed in descending order of importance (VIP) in the PLS-DA model. Between parentheses are reported the species used in the gel marker that run parallel to specific TTGE bands.
  2. (a) Mann-Whitney U-test, α = 0.05
  3. (b) Wilcoxon signed rank test, α = 0.05