TY - JOUR AU - Hasebe, Rie AU - Suzuki, Tadaki AU - Makino, Yoshinori AU - Igarashi, Manabu AU - Yamanouchi, Satoko AU - Maeda, Akihiko AU - Horiuchi, Motohiro AU - Sawa, Hirofumi AU - Kimura, Takashi PY - 2010 DA - 2010/06/08 TI - Transcellular transport of West Nile virus-like particles across human endothelial cells depends on residues 156 and 159 of envelope protein JO - BMC Microbiology SP - 165 VL - 10 IS - 1 AB - West Nile virus (WNV) causes viremia after invasion to the hosts by mosquito bite. Endothelial cells could play an important role in WNV spread from the blood stream into the central nervous system and peripheral tissues. Here, we analyzed the capacity of virus-like particles (VLPs) of the highly virulent NY99 6-LP strain (6-LP VLPs) and the low virulence Eg101 strain (Eg VLPs) to cross cultured human endothelial cells. SN - 1471-2180 UR - https://doi.org/10.1186/1471-2180-10-165 DO - 10.1186/1471-2180-10-165 ID - Hasebe2010 ER -