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Table 1 Prevention of recurrent HSV-2 infection in guinea pigs immunized with CJ9-gD

From: Immunization with a dominant-negative recombinant Herpes Simplex Virus (HSV) type 1 protects against HSV-2 genital disease in guinea pigs

 

Mock (n = 3)

CJ9-gD (n = 8)

Recurrency1

3/3

0/8

Recurrent lesions2

1/3

0/8

Recurrent shedding3

2/3

0/8

  1. 1 Overall number of guinea pigs with recurrent lesions and/or recurrent shedding between days 30 and 60 after challenge.
  2. 2 Number of guinea pigs with recurrent genital lesion between days 30 and 60 after challenge.
  3. 3 Number of guinea pigs from which virus was detected in vaginal swab material by plaque assay on Vero cell monolayers between days 30 and 60 after challenge.