Figure 1

Survival after skin inoculation with GAS isolates with different NADase activities. The survival times of 28 and 43 mice infected with GAS isolates belonging to low- and high-activity groups in Table 2, respectively, were shown. In addition, the survival time of mice infected with strain SF370 belonging to the no-activity group was also shown as a reference, since it is possible that the old strain differs considerably in genetic background compared with the other more contemporary eight isolates of Table 2 as described previously [7].