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Table 2 Viable counts of P. aeruginosa biofilm bacteria treated with NAC combined with ciprofloxacin (lg [CFU/cm2])

From: N-acetylcysteine inhibit biofilms produced by Pseudomonas aeruginosa

NAC (mg/ml)

ciprofloxacin (MIC)

 

0

1/2

1

2

4

8

0

7.11 ± 0.34

6.96 ± 0.34

6.95 ± 0.31

6.84 ± 0.32

6.76 ± 0.29

6.60 ± 0.30

0.5

6.97 ± 0.31

6.70 ± 0.31

6.65* ± 0.33

6.40* ± 0.46

6.37* ± 0.33

6.06* ± 0.48

1

6.87 ± 0.34

6.58* ± 0.26

6.47* ± 0.33

6.23* ± 0.37

5.94* ± 0.56

5.62* ± 0.59

2.5

6.45* ± 0.27

6.22* ± 0.25

6.15* ± 0.26

6.03* ± 0.35

5.76* ± 0.58

5.05* ± 0.35

  1. Note: n = 20 strains, *compared with NAC at 0 mg/ml and the same concentration of ciprofloxacin, P < 0.01