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Table 1 Functional classification of the identified M. tuberculosis H37Rv proteins.

From: Definition of novel cell envelope associated proteins in Triton X-114 extracts of Mycobacterium tuberculosis H37Rv

Functional group a Functional group no. Total protein number b Number of observed proteins c
Virulence, detoxification, adaptation 0 212 44 (21%)
Lipid metabolism 1 237 84 (35%)
Information pathways 2 232 98 (42%)
Cell wall and cell processes 3 751 313 (42%)
Stable RNAs 4 50 0 (0%)
Insertion sequences and phages 5 147 0 (0%)
PE/PPE 6 168 14 (8%)
Intermediary metabolism and respiration 7 898 412 (46%)
Unknown 8 15 0 (0%)
Regulatory proteins 9 194 54 (28%)
Conserved hypotheticals 10 895 299 (33%)
Conserved hypotheticals with an orthologue in M. bovis 16 262 52 (20%)
  1. a The functional groups were taken from the Tuberculist database, publically available at http://genolist.pasteur.fr/TubercuList/.
  2. b Total number of proteins in each group predicted in the genome.
  3. c Number of proteins identified and the ratio compared to the total number of proteins assigned to each functional group.