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Table 1 Passage history and titer (in C6/36 cells) of the 12 dengue virus strains used in this study

From: RNA interference modulates replication of dengue virus in Drosophila melanogaster cells

Serotype

Strain ID

Country of isolation

Source

Collection Year

Passage History1

Titer (log10

pfu/ml)

Obtained from2

DENV-1

JKT 85-1415

Indonesia

Human serum

1985

C6/36 p2

7.2

WRCEVA

DENV-1

1335 TVP

Sri Lanka

Human serum

1981

Inoculated mosquito-1X, C6/36 p2

7.2

WRCEVA

DENV-1

AusHT15

Australia

Human serum

1983

C6/36 p2

7.5

WRCEVA

DENV-2

Tonga/1974

Tonga

Human serum

1974

Mosquito-1X, C6/36 p5

8.0

NIAID

DENV-2

DOO-0372

Thailand

Human serum

1988

Previous history unknown, C6/36 p8

8.0

NIAID

DENV-2

NGC Proto

New Guinea

Human serum

1944

Inoculated monkey- 1X

7.5

NIAID

DENV-3

89 SriLan

1: D2783

Sri Lanka

Human serum

1989

C6/36 p2

7.6

UNC

DENV-3

89 SriLan 2: D1306

Sri Lanka

Human serum

1983

C6/36 p2

7.6

UNC

DENV-3

Sleman/78

Indonesia (Java)

Human serum

1978

Mosquito-1X, Vero p2, C6/36 p4

7.2

NIAID

DENV-4

1228 TVP

Indonesia

Human serum

1978

Mosquito p2, C6/36 p2

7.1

WRCEVA

DENV-4

779157

Taiwan

Human serum

1988

C6/36 p5

7.4

WRCEVA

DENV-4

BeH 403714

Brazil

Human serum

1982

C6/36 p3

7.2

WRCEVA

  1. 1cell type for passage followed by total number of passages (p) in that cell type
  2. 2 WRCEVA: provided by Dr. Robert Tesh at the World Reference Center of Emerging Viruses and Arboviruses at the University of Texas at Galveston (UTMB); NIAID: provided by Dr. Stephen Whitehead, NIAID, NIH; UNC: provided by Dr. Aravinda de Silva, Department of Microbiology and Immunology, University of North Carolina.