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Table 4 Amino acid changes encoded by mutations in gyrA, gyrB, parC, and parE in E. coli

From: In vitro selection of resistance in Escherichia coli and Klebsiella spp. at in vivo fluoroquinolone concentrations

 

Replacement in QRDR

Drug

GyrA

GyrB

ParC

ParE

LVX

(n = 4)

Ser83Leu (4)

Asp87Asn (4)

-

-

-

CIP

(n = 5)

Ser83Leu (5)

-

Ser80Ile (5)

-

PRU

(n = 7)

Ser83Leu (7)

-

Ser80Ile (7)

-

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BMC Microbiology

ISSN: 1471-2180

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