Skip to main content

Table 2 Differentially expressed flagellar genes in the HP0256 mutant.

From: The HP0256 gene product is involved in motility and cell envelope architecture of Helicobacter pylori

Proposed Class

TIGR orf no.

Putative gene product (gene)

Expression ratio

p-value

Class I

HP0019

chemotaxis protein (cheV)

1.221

0.026

 

HP0082

methyl-accepting chemotaxis transducer (tlpC)

0.945

0.378

 

HP0099

methyl-accepting chemotaxis protein (tlpA)

1.401**

0.112

 

HP0103

methyl-accepting chemotaxis protein (tlpB)

1.403**

0.05

 

HP0173

flagellar biosynthetic protein (fliR)

1.000

0.997

 

HP0244

signal-transducing protein, histidine kinase (atoS)

1.221

0.651

 

HP0246

flagellar basal-body P-ring protein (flgI)

-

-

 

HP0325

flagellar basal-body L-ring protein (flgH)

1.113

0.050

 

HP0326

CMP-N-acetylneuraminic acid synthetase (neuA)

0.904

0.219

 

HP0327

flagellar protein G (flaG)

0.749

0.238

 

HP0351

basal body M-ring protein (fliF)

0.889

0.508

 

HP0352

flagellar motor switch protein (fliG)

1.158

0.176

 

HP0391

purine-binding chemotaxis protein (cheW)

1.668**

0.004

 

HP0392

histidine kinase (cheA)

1.202

0.113

 

HP0393

chemotaxis protein (cheV)

1.176

0.194

 

HP0584

flagellar motor switch protein (fliN)

1.758**

0.042

 

HP0599

hemolysin secretion protein precursor (hylB)

1.201

0.366

 

HP0616

chemotaxis protein (cheV)

1.159**

0.162

 

HP0684

flagellar biosynthesis protein (fliP)

0.510

0.058

 

HP0685

flagellar biosynthetic protein (fliP)

0.493

0.066

 

HP0703

response regulator

0.715

0.158

 

HP0714

RNA polymerase sigma-54 factor (rpoN)

1.104

0.699

 

HP0770

flagellar biosynthetic protein (flhB)

0.621

0.162

 

HP0815

flagellar motor rotation protein (motA)

0.917

0.538

 

HP0816

flagellar motor rotation protein (motB)

0.651

0.231

 

HP0840

flaA1 protein

1.296

0.184

 

HP1041

flagellar biosynthesis protein (flhA)

0.988

0.921

 

HP1067

chemotaxis protein (cheY)

0.958

0.905

 

HP1092

flagellar basal-body rod protein (flgG)

1.142

0.140

 

HP1286

conserved hypothetical secreted protein (fliZ)

1.305

0.544

 

HP1419

flagellar biosynthetic protein (fliQ)

0.636

0.036

 

HP1420

flagellar export protein ATP synthase (fliI)

0.687

0.012

 

HP1462

secreted protein involved in flagellar motility

1.306

0.003

 

HP1575

homolog of FlhB protein (flhB2)

1.445

0.239

 

HP1585

flagellar basal-body rod protein (flgG)

0.590

0.019

Class II

HP0114

hypothetical protein

1.230

0.357

 

HP0115

flagellin B (flaB)

1.906

0.032

 

HP0295

flagellin B homolog (fla)

1.734

0.179

 

HP0869

hydrogenase expression/formation protein (hypA)

1.307

0.109

 

HP0870

flagellar hook (flgE)

1.892*

0.067

 

HP0906

hook length control regulator (fliK)

1.13**

0.230

 

HP1076

hypothetical protein

2.595

0.001

 

HP1119

flagellar hook-associated protein 1 (HAP1) (flgK)

1.300

0.224

 

HP1120

hypothetical protein

1.199

0.390

 

HP1154

hypothetical protein (operon with murG)

1.514

0.055

 

HP1155

transferase, peptidoglycan synthesis (murG)

1.955

0.034

 

HP1233

putative flagellar muramidase (flgJ)

1.400

0.144

Class III

HP0472

outer membrane protein (omp11)

1.649

0.009

 

HP0601

flagellin A (flaA)

1.487

0.229

 

HP1051

hypothetical protein

1.098

0.501

 

HP1052

UDP-3-0-acyl N-acetylglucosamine deacetylase (envA)

1.648

0.054

Intermediate

HP0165

hypothetical protein

1.226

0.515

 

HP0166

response regulator (ompR)

1.596

0.057

 

HP0366

spore coat polysaccharide biosynthesis protein C

0.860

0.419

 

HP0367

hypothetical protein

1.853

0.008

 

HP0488

hypothetical protein

0.711**

0.031

 

HP0907

hook assembly protein, flagella (flgD)

1.271

0.214

 

HP0908

flagellar hook (flgE)

1.175

0.119

 

HP1028

hypothetical protein

0.852

0.286

 

HP1029

hypothetical protein

0.799

0.019

 

HP1030

fliY protein (fliY)

0.860**

0.308

 

HP1031

flagellar motor switch protein (fliM)

0.835

0.054

 

HP1032

alternative transcription initiation factor, sigma28 (fliA)

0.923

0.371

 

HP1033

hypothetical protein

0.896

0.467

 

HP1034

ATP-binding protein (ylxH)

0.87**

0.352

 

HP1035

flagellar biosynthesis protein (flhF)

0.921

0.187

 

HP1122

anti-sigma 28 factor (flgM)

0.867

0.310

 

HP1440

hypothetical protein

0.627

0.026

 

HP1557

flagellar basal-body protein (fliE)

0.652

0.091

 

HP1558

flagellar basal-body rod protein (flgC) (proximal rod protein)

0.899

0.480

 

HP1559

flagellar basal-body rod protein (flgB) (proximal rod protein)

1.305

0.194

 

HP0751

(flaG2)

1.203

0.350

 

HP0752

flagellar cap protein (fliD)

1.003

0.986

 

HP0753

flagellar chaperone (fliS)

0.981

0.825

 

HP0754

flagellar chaperone (fliT)

1.09**

0.400

Not assigned

HP0410

flagellar sheath associated protein (hpaA2)

0.664

0.038

 

HP0492

flagellar sheath associated protein (hpaA3)

0.256

0.000

 

HP0797

flagellar sheath associated protein (hpaA)

0.801

0.170

  1. Full array datasets are in public databases as described in Methods. Fold-changes and p-values were calculated based on 4 independent biological replicates as described in Methods. Open reading frames and gene annotations were based on the TIGR database [23]. The genes were classified in different flagellar classes, as previously proposed [8]. Confirmatory analysis by qRT-PCR was performed for genes with *. Values for genes with ** were lost during the initial array data analysis and subsequently recovered using 3 independent replicates. For technical reasons, some array spots could not be analyzed in individual arrays.
Back to article page

BMC Microbiology

ISSN: 1471-2180

Contact us