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Table 1 Gene list of significantly up- and down-regulated genes in the HP0256 mutant based on the array experiment.

From: The HP0256 gene product is involved in motility and cell envelope architecture of Helicobacter pylori

TIGR orf no. Putative gene product (gene) Expression ratio p-value
Down-regulated genes:
Hp26695-0092 type II restriction enzyme M protein (hsdM) 0.15 0.02
HpJ99-1132 dimethyladenosine transferase 0.17 0.00
Hp26695-0093 alpha-2-fucosyltransferase 0.22 0.01
Hp26695-0229 outer membrane protein (omp6) ( hopA ) 0.24 0.01
Hp26695-0492 flagellar sheath associated protein ( hpaA3 ) 0.26 0.00
Hp26695-1210 serine acetyltransferase (cysE) 0.26 0.00
Hp26695-1587 conserved hypothetical protein 0.27 0.00
Hp26695-1208 ulcer associated adenine specific DNA methyltransferase 0.27 0.00
Hp26695-0610 toxin-like outer membrane protein 0.32 0.03
Hp26695-1207 hypothetical protein 0.34 0.01
HpJ99-0055 putative 0.35 0.03
Hp26695-1211 hypothetical protein 0.37 0.00
Hp26695-0430 hypothetical protein 0.40 0.04
Hp26695-1492 conserved hypothetical nifU-like protein 0.41 0.01
Hp26695-0805 lipooligosaccharide 5G8 epitope biosynthesis-associated protein 0.42 0.02
Hp26695-1203a Preprotein translocase subunit SecE 0.43 0.01
Hp26695-1219 hypothetical protein 0.43 0.04
Hp26695-0711 hypothetical protein 0.45 0.01
Hp26695-1180 pyrimidine nucleoside transport protein (nupC) 0.46 0.03
Hp26695-0502 hypothetical protein 0.46 0.03
Hp26695-1589 conserved hypothetical protein 0.47 0.01
Hp26695-0094 alpha-2-fucosyltransferase 0.49 0.02
Hp26695-1334 hypothetical protein 0.49 0.01
Hp26695-0415 conserved hypothetical integral membrane protein 0.49 0.01
Hp26695-0340 hypothetical protein 0.49 0.00
Hp26695-0798 molybdenum cofactor biosynthesis protein C (moaC) 0.49 0.03
Hp26695-0892 conserved hypothetical protein 0.50 0.03
Hp26695-0331 cell division inhibitor ( minD ) 0.59 0.04
Up-regulated genes:
Hp26695-0115 flagellin B ( flaB ) 1.91 0.03
Hp26695-0979 cell divison protein ( ftsZ ) 1.92 0.00
Hp26695-1469 outer membrane protein ( omp31 ) ( hopV ) 1.96 0.00
Hp26695-1243 outer membrane protein ( omp28 ) ( babA ) 1.96 0.00
Hp26695-0386 hypothetical protein 2.01 0.00
Hp26695-0831 conserved hypothetical ATP binding protein 2.04 0.01
Hp26695-0952 conserved hypothetical integral membrane protein 2.05 0.00
Hp26695-0311 hypothetical protein 2.16 0.00
Hp26695-0720 hypothetical protein 2.16 0.02
Hp26695-0943 D-amino acid dehydrogenase (dadA) 2.18 0.01
Hp26695-0896 outer membrane protein ( omp19 ) ( babB ) 2.18 0.00
Hp26695-0590 ferredoxin oxidoreductase, beta subunit 2.23 0.01
Hp26695-0589 ferredoxin oxidoreductase, alpha subunit 2.27 0.01
Hp26695-1340 biopolymer transport protein ( exbD ) 2.30 0.00
Hp26695-1339 biopolymer transport protein ( exbB ) 2.36 0.00
Hp26695-0747 conserved hypothetical protein 2.44 0.03
Hp26695-0310 conserved hypothetical protein 2.48 0.00
Hp26695-1322 hypothetical protein 2.57 0.03
Hp26695-1076 hypothetical protein 2.59 0.00
Hp26695-1524 hypothetical protein 2.68 0.05
Hp26695-0721 hypothetical protein 2.99 0.00
Hp26695-0744 pseudogene 3.08 0.00
Hp26695-0719 hypothetical protein 3.34 0.01
Hp26695-0954 oxygen-insensitive NAD(P)H nitroreductase 3.53 0.00
  1. The fold-change and the p-value are indicated. Bold fonts were used to highlight genes considered biologically relevant for the present study (surface-or motility-related genes). Full array datasets are in public databases as described in Methods.