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Table 4 Rat AM genes up-regulated by dexamethasone and further up-regulated by Pneumocystis infection

From: Microarray studies on effects of Pneumocystis carinii infection on global gene expression in alveolar macrophages

Gene

D vs. N

Pc vs. D

S100a9

2.65

11.55

S100a8

2.50

6.52

RT1-Bb

3.98

5.42

RT1-Db1

1.65

5.35

Srgn

3.39

5.34

Ass1

1.62

5.28

Apoe

2.47

5.23

Cd74

4.50

4.95

RT1-Da

6.15

4.35

Fn1

10.19

4.20

Il1r2

3.50

3.14

Enpp3

2.08

2.88

Slc28a2

8.24

2.71

F3

2.87

2.67

Ccl2

9.99

2.65

C1qb

2.04

2.64

Pon1

3.05

2.29

Il1b

8.65

2.26

Nudt4

3.48

2.15

Cd14

8.10

1.85

Ptafr

1.59

1.84

Arg1

1.60

1.83

Ptgs2

2.01

1.83

Pstpip1

3.29

1.79

Pde4b

1.88

1.76

Xdh

5.55

1.74

Socs2

1.73

1.67

Bst1

2.34

1.55

Gda

2.26

1.55

Ctsk

3.68

1.54

Emb

1.71

1.53

Ptpn1

2.46

1.50

  1. Values shown are fold changes. D vs. N: expression affected by dexathamethasone (D) treatment compared to the normal control (N); Pc vs. D: expression affected by Pneumocystis (Pc) infection compared to the Dex (D) control.