Table 1 Genes involved in the four major AM functions affected by Pneumocystis infection
Gene | Pc vs. D | Immune Response (23 genes) | Inflammation (23 genes) | Cell Death (29 genes) | Phagocytosis (25 genes) |
|---|---|---|---|---|---|
Lgals1 | -4.24 | ↓ | ↓ | ↓ | ↓ |
Alcam | -2.29 | ↓ | ↓ | ↓ | ↓ |
Cd55 | -1.68 | ↓ | ↓ | ↓ | ↓ |
Cat | -1.64 | NA | NA | ↓ | ↓ |
Hip1 | -1.63 | NA | NA | ↓ | ↓ |
Hdac2 | -1.61 | NA | NA | ↓ | NA |
Bnip3l | -1.58 | NA | NA | ↓ | NA |
Nr1h3 | -1.52 | NA | NA | ↓ | NA |
Ppp6c | -1.52 | NA | NA | ↓ | NA |
Sod2 | 1.50 | ↑ | ↑ | ↑ | ↑ |
Socs3 | 1.67 | ↑ | ↑ | ↑ | ↑ |
Tap2 | 1.67 | NA | NA | ↑ | NA |
Mmp14 | 1.78 | NA | ↑ | ↑ | ↑ |
Prf1 | 1.78 | ↑ | ↑ | ↑ | ↑ |
Il10 | 1.87 | ↑ | ↑ | ↑ | ↑ |
Mmp7 | 1.92 | ↑ | ↑ | ↑ | ↑ |
Mx2 | 1.94 | ↑ | NA | NA | ↑ |
Sell | 1.97 | ↑ | ↑ | ↑ | ↑ |
Psmb9 | 2.14 | ↑ | ↑ | ↑ | ↑ |
Oas1a | 2.32 | ↑ | ↑ | ↑ | ↑ |
Mmp8 | 2.34 | NA | ↑ | ↑ | ↑ |
Clu | 2.37 | ↑ | ↑ | ↑ | ↑ |
Ccr1 | 2.40 | ↑ | ↑ | ↑ | ↑ |
Mx1 | 2.42 | ↑ | ↑ | ↑ | ↑ |
Il8rb | 2.78 | ↑ | ↑ | ↑ | ↑ |
Ccr5 | 2.79 | ↑ | ↑ | ↑ | ↑ |
Gbp2 | 3.21 | ↑ | ↑ | NA | NA |
Tap1 | 3.47 | ↑ | NA | NA | NA |
Ccl5 | 3.58 | ↑ | ↑ | ↑ | ↑ |
Irf7 | 4.92 | ↑ | ↑ | ↑ | ↑ |
Nos2 | 6.35 | ↑ | ↑ | ↑ | ↑ |
Cxcl10 | 12.33 | ↑ | ↑ | ↑ | ↑ |