Virulence-related Mycobacterium avium subsp hominissuis MAV_2928 gene is associated with vacuole remodeling in macrophages

Table 4 Concentrations of single elements in phagosomes of macrophages infected with M. avium wild-type (WT) or 2D6 mutant

Element (Unit)	WT	2D6	WT	2D6
	1 hour		24 hours
P (CPM)	0.013964	0.0144769	0.010927	0.0072144
	(p > 0.05)		(p > 0.05)
S (CPM)	0.01848	0.0210543	0.035871	0.0099751
	(p > 0.05)		(p > 0.05)
Cl (CPM)	0.151509	0.2305818	0.244938	0.1115413
	(p > 0.05)		(p > 0.05)
K (μg/cm²)	0.143707	0.3204288	0.021604	0.1759281
	(p = 0.05)		(p = 0.0009)
Ca (μg/cm²)	6.5 × 10^-5	0.0329014	0.010014	0.0224007
	(p = 0.821)		(p = 0.00492)
Mn (μg/cm²)	6.5 × 10^-5	0.00018	0.000133	8.204 × 10^-5
	(p = 0.0308)		(p = 0.302)
Fe (μg/cm²)	0.00167	0.0054284	0.006516	0.0022057
	(p = 0.3025)		(p = 0.12196)
Cu (μg/cm²)	0.000183	0.1394013	0.000112	0.0148152
	(p > 0.05)		(p > 0.05)
Zn (μg/cm²)	0.00088	0.015652	0.000792	0.005898
	(p = 0.00517)		(p = 0.02767)

Complemented 2D6 mutant had similar results to the wild-type bacterium. Y = Yes; N = No

ISSN: 1471-2180