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Table 4 Concentrations of single elements in phagosomes of macrophages infected with M. avium wild-type (WT) or 2D6 mutant

From: Virulence-related Mycobacterium avium subsp hominissuis MAV_2928 gene is associated with vacuole remodeling in macrophages

Element
(Unit)
WT 2D6 WT 2D6
  1 hour 24 hours
P (CPM) 0.013964 0.0144769 0.010927 0.0072144
  (p > 0.05) (p > 0.05)
S (CPM) 0.01848 0.0210543 0.035871 0.0099751
  (p > 0.05) (p > 0.05)
Cl (CPM) 0.151509 0.2305818 0.244938 0.1115413
  (p > 0.05) (p > 0.05)
K (μg/cm2) 0.143707 0.3204288 0.021604 0.1759281
  (p = 0.05) (p = 0.0009)
Ca (μg/cm2) 6.5 × 10-5 0.0329014 0.010014 0.0224007
  (p = 0.821) (p = 0.00492)
Mn (μg/cm2) 6.5 × 10-5 0.00018 0.000133 8.204 × 10-5
  (p = 0.0308) (p = 0.302)
Fe (μg/cm2) 0.00167 0.0054284 0.006516 0.0022057
  (p = 0.3025) (p = 0.12196)
Cu (μg/cm2) 0.000183 0.1394013 0.000112 0.0148152
  (p > 0.05) (p > 0.05)
Zn (μg/cm2) 0.00088 0.015652 0.000792 0.005898
  (p = 0.00517) (p = 0.02767)
  1. Complemented 2D6 mutant had similar results to the wild-type bacterium. Y = Yes; N = No