Figure 1

Upregulation of U937 macrophage genes upon infection with M. avium or 2D6 mutant at 4 h, as determined by real-time PCR. U937 were infected with MAC 109 or MAC 2D6. Four hours later, macrophage RNA was purified and used for real-time PCR to measure the expression of GRK4, DGKD and LCP2. The data represent the average of three independent experiments ± SD. A p < 0.05 for the three genes compared with the regulation in the other strain.