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Table 2 Phenotypic analysis of wild type Streptococcus pyogenes isolate CS101, an isogenic sagA/pel::Tn 917 mutant and a kidney-recovered variant of the sagA/pel::Tn917 mutant.

From: Mouse skin passage of a Streptococcus pyogenes Tn917 mutant of sagA/pel restores virulence, beta-hemolysis and sagA/pel expression without altering the position or sequence of the transposon

  Strains
Phenotype Wild Type sagA/pel ::Tn 917 Kidney-recovered sagA/pel ::Tn 917
Beta hemolysis SLS + - +
SK + - -
Cysteine protease, SpeB ++ - -
Fibrinogen binding % + ± ++
Fibronectin binding % + ± +
  1. ++ = > 50% more than the wild type + = wild type levels ± = 15 – 30% of the wild type level - = < 10% of the wild type
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BMC Microbiology

ISSN: 1471-2180

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