Map of the M. tuberculosis H37Rv DNA integrated in the sur2 genome. The integrated 4 kb cosmid is between the two attachment sites, attL and attR. The 4.4 kb Pst I fragment of sur2 is indicated by the two Pst I sites. The 1,106 bp M. tuberculosis H37Rv genomic DNA insert contains two ORFs designated Rv0365c and Rv0366c [Reference 23]. The arrows indicate the direction of transcription. Arrows are color coded according to annotations found on the TubercuList server http://genolist.Pasteur.fr/TubercuList/: light green (unknown), brown (conserved), yellow (intermediary metabolism), light blue (regulatory), gray (virulence), red (information pathway), dark green (cell wall process), black (lipid metabolism), and dark blue (stable RNA).