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Table 2 Bactericidal and Opsonophagocytic Activity of monoclonal antibodies raised against IROMPs of A. baumannii. The antibodies were tested for both type of bacteria i.e. bacteria grown in CDM-Fe and CDM+Fe medium. Results are the mean of three independent experiments in both the cases. ± represents the standard deviation.

From: Monoclonal antibodies against the iron regulated outer membrane Proteins of Acinetobacter baumannii are bactericidal

Antibodies/ Bactericidal Bactericidal No. of Bacteria No. of Bacteria
Various Controls Activity in Activity in grown in CDM- grown in CDM-
  CDM-Fe CDM+Fe Fe medium per Fe medium per
  medium(%) medium(%) PMN PMN
2G9ABIR 98.0% ± 8.0% 15.0% ± 4% 9.0 ± 2.0 2.0 ± 1.0
3D5ABIR 97.0% ± 12.0% 22.0% ± 9% 11.0 ± 3.5 2.0 ± 0.5
5D6ABIR 90.0% ± 11.0% 9.00% ± 4% 10.5 ± 2.5 1.0 ± 0.5
1D11ABIR 97.0% ± 17% 19.00% ± 6% 9.0 ± 1.5 3.0 ± 1.0
1F7ABIR+ 93.0% ± 5% 26.0% ± 12% 10.0 ± 1.5 3.0 ± 1.8
Preimmune Sera 12.0% ± 2% 16.0% ± 6% 1.5 ± 0.5 2.5 ± 1.0
Complement only 12.0% ± 5% 8.50% ± 1% - -
Tissue culture 24.0% ± 7% 21.0% ± 4% 2.0 ± 0.5 1.5 ± 0.2
supernatant only     
Polyclonal Sera 68.0% ± 13% 39.0% ± 7% 7.0 ± 1.0 4.5 ± 1.0
Only PBS 1.0% ± 1% 2.0% ± 1.5% 1 ± 0.2 1 ± 0.5