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Table II Demographic and clinical data of the anti-HBe positive patients.

From: Low frequency of mutations in the core promoter and precore regions of hepatitis B virus in anti-HBe positive Brazilian carriers

     Nucleotides at positions No. of substitutionsa
Genotype Patient Age/Sex Clinical status 1762-1764 1858 1896 CPMs UPMs
A A1 55/M Cirrhosis AGG C G 0 0
  A2 41/F Cirrhosis AGG C G 0 0
  A3 45/M Cirrhosis, HCC AGG C G 0 1
  A4 40/F Cirrhosis AGG C G 0 0
  A5 10/F Asymptomatic TGA (mutant) C G 1 6
  A6 52/M CAH TGA (mutant) C G 1 8
  A7 38/M CAH AGG C G 0 2
  A8 54/M Cirrhosis AGG C G 0 0
  A9 52/M CAH AGG C G 0 4
  A10 39/M Asymptomatic AGG C G 0 0
D D1 36/M CAH AGG T G 0 2
  D2 54/F Asymptomatic TGA (mutant) T A (stop) 2 7
  D3 56/F CAH TGA (mutant) T A (stop) 2 13
  D4 35/M Cirrhosis TGA (mutant) T A (stop) 2 5
  D5 55/M CAH TGA (mutant) T A (stop) 2 8
  D6 47/M Asymptomatic AGG T G 0 6
  D7 53/M Asymptomatic AGG T G 0 6
F F1 10/M Asymptomatic AGG C G 0 7
  F2 35/M CAH AGG T A (stop) 1 8
  1. aNumber of common (CPMs) and uncommon (UPMs) point mutations (see text) in a 200-bp genome segment, from nt 1720 to nt 1919