Microbe-host interactions and microbial pathogenicity

Section edited by David Nelson

This section aims to publish studies looking at all aspects of microbe-host interactions and pathogenicity including pathogenic mechanisms, virulence factors, host invasion, immune evasion, host defence, immunity, immunology and symbiotic interactions.

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  1. Research article

    An avirulent Burkholderia pseudomalleipurM strain with atypical type B LPS: expansion of the toolkit for biosafe studies of melioidosis

    The work was undertaken to expand the tools available for researching Burkholderia pseudomallei (Bp), the etiological agent of the tropical disease melioidosis. Melioidosis has the potential to pose a severe thre...

    Michael H. Norris, Md Siddiqur Rahman Khan, Herbert P. Schweizer and Apichai Tuanyok

    BMC Microbiology 2017 17:132

    Published on: 7 June 2017

  2. Research article

    Cytotoxic Necrotizing Factor-1 (CNF1) does not promote E. coli infection in a murine model of ascending pyelonephritis

    Urinary tract infections (UTI) are among the most common and costly infections in both hospitalized and ambulatory patients. Uropathogenic E. coli (UPEC) represent the majority of UTI isolates and are a diverse g...

    Jason E. Michaud, Kwang Sik Kim, William Harty, Matthew Kasprenski and Ming-Hsien Wang

    BMC Microbiology 2017 17:127

    Published on: 25 May 2017

  3. Research article

    Characterization of novel Omp31 antigenic epitopes of Brucella melitensis by monoclonal antibodies

    Brucellosis is a severe zoonotic disease worldwide. Detection and identification of Brucella species are essential to prevent or treat brucellosis in humans and animals. The outer membrane protein-31 (Omp31) is a...

    Jinfeng Li, Feihuan Hu, Shouyi Chen, Peifang Luo, Zuoping He, Wenjing Wang, Jean-Pierre Allain and Chengyao Li

    BMC Microbiology 2017 17:115

    Published on: 15 May 2017

  4. Research article

    DFI-seq identification of environment-specific gene expression in uropathogenic Escherichia coli

    During infection of the urinary tract, uropathogenic Escherichia coli (UPEC) are exposed to different environments, such as human urine and the intracellular environments of bladder epithelial cells. Each environ...

    Michelle Madelung, Tina Kronborg, Thomas Koed Doktor, Carsten Struve, Karen Angeliki Krogfelt and Jakob Møller-Jensen

    BMC Microbiology 2017 17:99

    Published on: 24 April 2017

  5. Research article

    Localization of Staphylococcus aureus in tissue from the nasal vestibule in healthy carriers

    Colonization of the body is an important step in Staphylococcus aureus infection. S. aureus colonizes skin and mucous membranes in humans and several animal species. One important ecological niche of S. aureus is...

    Anne-Merethe Hanssen, Bert Kindlund, Niels Christian Stenklev, Anne-Sofie Furberg, Silje Fismen, Renate Slind Olsen, Mona Johannessen and Johanna Ulrica Ericson Sollid

    BMC Microbiology 2017 17:89

    Published on: 5 April 2017

  6. Research article

    Supplemental invasion of Salmonella from the perspective of Salmonella enterica serovars Kentucky and Typhimurium

    Critical to the development of Salmonellosis in humans is the interaction of the bacterium with the epithelial lining of the gastrointestinal tract. Traditional scientific reasoning held type III secretion sys...

    Kevin Howe, Sanaz Salehi, R. Hartford Bailey, John P. Brooks, Robert Wills, Mark L. Lawrence and Attila Karsi

    BMC Microbiology 2017 17:88

    Published on: 5 April 2017

  7. Research article

    Uropathogenic Escherichia coli pathogenicity islands and other ExPEC virulence genes may contribute to the genome variability of enteroinvasive E. coli

    Enteroinvasive Escherichia coli (EIEC) may be the causative agent of part of those million cases of diarrhea illness reported worldwide every year and attributable to Shigella. That is because both enteropathogen...

    Laís Cristina da Silva, Ana Carolina de Mello Santos and Rosa Maria Silva

    BMC Microbiology 2017 17:68

    Published on: 16 March 2017

  8. Research article

    Oral microbe-host interactions: influence of β-glucans on gene expression of inflammatory cytokines and metabolome profile

    The aim of this study was to evaluate the effects of β-glucan on the expression of inflammatory mediators and metabolomic profile of oral cells [keratinocytes (OBA-9) and fibroblasts (HGF-1) in a dual-chamber ...

    Viviam de Oliveira Silva, Luciano José Pereira and Ramiro Mendonça Murata

    BMC Microbiology 2017 17:53

    Published on: 7 March 2017

  9. Research article

    Genetic profiling for Anaplasma and Ehrlichia species in ticks collected in the Eastern Cape Province of South Africa

    Anaplasma and Ehrlichia are emerging tick-borne pathogens that cause anaplasmosis and ehrlichiosis in humans and other animals worldwide. Infections caused by these pathogens are deadl...

    Benson C. Iweriebor, Elia J. Mmbaga, Abiodun Adegborioye, Aboi Igwaran, Larry C. Obi and Anthony I. Okoh

    BMC Microbiology 2017 17:45

    Published on: 27 February 2017

  10. Research article

    Porphyromonas gingivalis can invade periodontal ligament stem cells

    Porphyromonas gingivalis is strongly associated with the development, progression, severity and recurrence of periodontitis. Periodontal ligament stem cells (PDLSCs) play an important ...

    Chunling Pan, Junchao Liu, Hongyan Wang, Jia Song, Lisi Tan and Haijiao Zhao

    BMC Microbiology 2017 17:38

    Published on: 17 February 2017

  11. Researc article

    Bacterial microbiota of Kazakhstan cheese revealed by single molecule real time (SMRT) sequencing and its comparison with Belgian, Kalmykian and Italian artisanal cheeses

    In Kazakhstan, traditional artisanal cheeses have a long history and are widely consumed. The unique characteristics of local artisanal cheeses are almost completely preserved. However, their microbial communi...

    Jing Li, Yi Zheng, Haiyan Xu, Xiaoxia Xi, Qiangchuan Hou, Shuzhen Feng, Laga Wuri, Yanfei Bian, Zhongjie Yu, Lai-Yu Kwok, Zhihong Sun and Tiansong Sun

    BMC Microbiology 2017 17:13

    Published on: 9 January 2017

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