Open Access

Erratum to: Surveillance of pyrazinamide susceptibility among multidrug-resistant Mycobacterium tuberculosis isolates from Siriraj Hospital, Thailand

  • Jirarut Jonmalung1,
  • Therdsak Prammananan2, 4,
  • Manoon Leechawengwongs3, 4 and
  • Angkana Chaiprasert1, 4Email author
BMC Microbiology201010:278

DOI: 10.1186/1471-2180-10-278

Received: 28 October 2010

Accepted: 9 November 2010

Published: 9 November 2010

The Research article to this article has been published in BMC Microbiology 2010 10:223

Correction

After galley proof of the manuscript, we found three mistakes of the nucleotide positions (G222C, G364A and C520T) and codon numbers (Gly74Arg, Gly122Ser and Thr174Ile) that have to be corrected but it was unable to make any change because the publication of this work is on going [1]. After revision, Table two (Table 1 in this manuscript) and some information in the discussion part were changed. There were only 5 novel mutation types found in this study, consisting of 2 nucleotide substitutions (Leu27Pro and Thr174Ile), 2 nucleotide insertions (G insertion between nucleotide 411 and 412 and GG insertion between nucleotide 520 and 521), and 1 nonsense mutation at Glu127.
Table 1

Results of pncA gene sequencing of 150 M. tuberculosis clinical isolates.

   

pncA mutation

M. tuberculosis strains (no. of isolates)

MGIT 960

PZase assay

Nucleotide change

Amino acid change

Susceptible (46)

S

+

wild-type

no

Susceptible (1)

S

+

T92G

Ile31Ser

Susceptible (2)

R

+

wild-type

wild-type

Susceptible (1)

R

+

T92C

Ile31Thr

MDR-TB (42)

S

+

wild-type

wild-type

MDR-TB (9)

S

+

T92C

Ile31Thr

MDR-TB (34)

R

-

A(-11)G (1)

no

   

A(-11)C (1)

no

   

T56G (1)

Leu19Arg

   

T80C (1)

Leu27Pro

   

T92G (2)

Ile31Ser

   

T104C (1)

Leu35Pro

   

T134C (1)

Val45Ala

   

G136T (1)

Ala46Ser

   

T199C (1)

Ser67Pro

   

C211G (8)

His71Asp

   

G215A (1)

Cys72Tyr

   

G289A (3)

Gly97Ser

   

C312G (2)

Ser104Arg

   

G322C (1)

Gly108Arg

   

G373T (1)

Val125Phe

   

G379T (1)

Glu 127 Stop

   

G394A (1)

Gly132Ser

   

G insertion b/w 411-412 (1)

 
   

T416G (1)

Val 139 Gly

   

C425T (1)

Thr 142 Met

   

G436A (1)

Ala 146 Thr

   

GG insertion b/w 520-521 (1)

 
   

C530T (1)

Thr 177 Ile

MDR-TB (11)

R

+

wild-type

no

MDR-TB (4)

R

+

T92C (3)

Ile31Thr

   

T92G (1)

Ile31Ser

We regret any inconvenience that the mistake might have caused. We wish to thank Dr. Claudio Köser, Department of Genetics, University of Cambridge, for bringing this matter to our attention.

Notes

Authors’ Affiliations

(1)
Department of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University
(2)
National Center for Genetic Engineering and Biotechnology, National Science and Technology, Development Agency, Ministry of Science and Technology
(3)
Vichaiyut Hospital
(4)
Drug-Resistant Tuberculosis Research Fund, Siriraj Foundation

References

  1. Jonmalung J, Prammananan T, Leechawengwongs M, Chaiprasert A: Surveillance of pyrazinamide susceptibility among multidrug-resistant Mycobacterium tuberculosis isolates from Siriraj Hospital, Thailand. BMC Microbiology. 2010, 10: 223-10.1186/1471-2180-10-223.PubMed CentralView ArticlePubMed

Copyright

© Jonmalung et al; licensee BioMed Central Ltd. 2010

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://​creativecommons.​org/​licenses/​by/​2.​0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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